Glucagon-like peptide-1 agonism - GLP-1, common in obesity medicines - is not essential to weight management, according to preclinical research led by Richard DiMarchi and Matthias Tschöp, with funding from their startup company Bluewater Biosciences.
Nah, it just leaves you in worse health with 2/3 of the weight gained back in less than a year after stopping. And likely keep gaining after that.
Bug Pharma got their opioids grift shut down, so they coincidentally found out this unrelated drug was a magic weight loss pill with no downsides?
It’s way more likely they’ve known from the start these drugs only work while taking.
They’re not selling 2-3 years of responsible drug use, people will be on these drugs for life, because they won’t stop if it means gaining weight.
Edit:
Actually, were at full weight regain in 2 years now…
https://www.health.harvard.edu/medications-and-treatments/weaning-off-a-glp-1-tips-for-the-transition
That’s on top of the cardiac damage, and how your blood sugar is even more fucked up…
People are paying all this money, fucking up their bodies…
For something that doesn’t work if you ever stop taking it
“If there’s no solution, there can still be a buck made by prolonging the problem.”
Elaborate on the negative health effects please because everyone I know that’s on them is having positive health effects, except some common side effects which aren’t permanent (fatigue, anhedonia).
In fact the main reason I hear people stop taking them is insurance coverage, but they’d continue if they could.
I’m talking about after they stop…
I thought that was pretty obvious.
It works like it’s supposed to while taking it, and your body adapts to it just like anything else. (Edit: well, there’s chronic fatigue, vomiting, vertigo, all sorts of shit, but people on it already know about that, and you should get warned before starting. What people don’t get warned about is after stopping. So that’s what I’m focusing on)
And when you stop your body doesn’t have what it’s used to, don’t forget this is a medicine for diabetes, it will change how your body regulates blood sugar, and without it, it’s not going to know what the fuck to do
https://medicine.washu.edu/news/stopping-glp-1-drugs-can-quickly-erase-cardiovascular-benefits/
That talks about cardiovascular issues, but again, remember that while this passed trials for diabetes treatment, there hasn’t been many long term studies about what happens to people who stop taking it. And as time goes on, more people that need it less try it.
All the studies are at ~2 years out after cessation, and those were the people who were seriously obese. The people who started later and just “chubby” are likely to see diminished gains, but the same damage. Damage that we have no reason to believe will stop accumulating after 2 years…
That’s just as far as we’ve studied, all this shit should have done before released to the public.
yea, but… $$$$$$$$
Here’s the gov.uk page on adverse effects: https://www.gov.uk/drug-safety-update/glp-1-receptor-agonists-reminder-of-the-potential-side-effects-and-to-be-aware-of-the-potential-for-misuse
82 deaths linked to averse reactions to GLP-1 agonists, BMJ: https://www.bmj.com/content/388/bmj.r390 Unfortunately not open access.
These drugs are bad for them? I had only heard of other benefits from them. No doubt a PR campaign, along with aggressively shutting down any negative stories/studies with the usual tactics, pioneered by big tobacco and now adopted by all the polluters and poisoners.