• bedwyr@piefed.ca
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    3 days ago

    As an aside, tolerance only goes so far, and it changes with the drug. I wish I still had the graphic I once read in the cursed nyt 20 some years back, that broke it down with major drugs, how much of a tolerance can be built. Opiates for example, I think are high, you can get a major tolerance compared with an opiate naive person, other drugs it is less so.