I read the whole article and that particular test was the least alarming to me. They say the cells died 3x faster than when exposed to a more diluted solution, but the article doesn’t mention references for what concentration levels were tested or if the levels were anywhere close to what a real human could be exposed to. They just say the particles might accumulate over time, but that doesn’t really mean anything without hard numbers.
This may be true, but I think the main reason for less “obvious” baddies in modern movies is simply that they kind of went out of fashion from a culture standpoint. The ways how stories are told and how world is portrayed/perceived in art and media is heavily dependent on the people who live in it. Post-modernism is en vogue because we’ve shifted our world view from simple good vs. bad towards recognizing that the world we live in is much more nuanced/complex. “Sometimes the villain is in your head” or “nothing really matters, everything sucks one way or another” are world views that reflect our modern western culture a lot more since we are so much more connected to the world through the internet.
That said, post/meta-modernism is just one side of this. I’m sure there are plenty of commercial reasons to make toothless, non-offending movies as well. Also, movies like Top Gun: Maverick prove that the classic approach to storytelling (good guys vs bad guys) can still work and make a shitton of cash (although they didn’t go all in on who the enemy actually is).