They are trying really hard to do something

It’s weird, when the keto and carnivore papers get published they are always open access… but this paper… closed… and doesn’t define their categories… it’s curious. If i wasn’t a charitable man I make think that was intentional.

I have lots of biases in the area the paper is talking about. I’ve acquired the actual paper and on first pass they don’t define what low carb means… really, they don’t, anywhere… including the supplemental material. Making best effort inferences on how they make the category cohorts, it seems 40% of energy from carbs is the cutoff. 40% of a 1800 calorie diet is about 200g of carbs per day.

Currently my smells on this paper

• Who : Harvard nutrition, a org with a history of heavy plant based bias
• What they said : PBF beats ABF in a 200g “low carb” diet using intermediate health metrics
• On the basis of what : Epidemiology, on food frequency questionaries, using major assume corrective factors
• In what context : 200g/day carb diet, not controlling for processed foods (so healthy user bias the unprocessed abf group isn’t represented at all)… they explicitly say this paper doesn’t apply to keto “evidence from our study regarding the LCD and LFD patterns cannot be directly generalized to diets with much lower carbohydrates or fats intake, such as the ketogenic diet.”

The bias is really evident in that they defined healthy and unhealthy LCD in terms of animal products… that is presupposing the outcomes in their healthy fat ranking system!

When I have more time I’ll do a full post on this paper after I’ve had time to read it and figure out what the actual data is. I’m gobsmacked a paper on low carb doesn’t even define what % of carbs is low carb explicitly… why make that so indirect and hidden!!!

The good news is harvard is finally acknowledging the tsunami of low carb and keto research in their own way, but they are going to do it kicking and screaming on the pbf hill the entire time… but progress is progress.

Anson Keys

Ancel Keys

Removed by mod

I think it’s often a short hand to get people to slow down and pay attention. Be careful! Take it slow, no rush.

Nice keyboard

Xmonad!

I get really weird feelings when I run brew …

Isn’t the debate on what the foreign court would accept as evidence and not what the DMCA intends to be evidence?

What’s even better if you go to the trouble of responding to them using other outdated phonetic glyphs they don’t even try to understand it… Talk about double standards

This is really cool. Thank you for sharing it

@[email protected]

Almost all checkups do a lipid panel. You just have to look at your triglycerides and your HDL, take the ratio of them TG over HDL. You want that to be less than two, and for bonus points you want that to be less than one. Anything above two you have room for improvement. This ratio is a fairly good analog for insulin sensitivity and metabolic health.

Signs of poor metabolic health:

• obesity
• high blood pressure
• Ed
• snoring
• fatty liver
• skin tags
• diabetes

The problem with a lot of these papers is they use intermediate endpoints rather than actual hard end points. They’re making the assumption that decreasing LDL is a good thing. That’s an intermediate endpoint, nobody actually cares about their LDL, they care about their health span and lifespan.

Spoiler: LDL and Cholesterol in general is not a disease, it’s poor metabolic health that is the actual cardiovascular problem.

I.e. https://doi.org/10.3390/metabo14010073 Oreo cookie treatment lowers LDL cholesterol more than high-intensity statin therapy in a lean mass hyper-responder on a ketogenic diet: a curious crossover experiment

This stunt paper illustrates how silly it is to focus on a intermediate metric. Oreos are not health food, I should hope that is obvious

My LDL is the only thing wrecking my score.

Cholesterol, and LDL specifically, are not a disease. If you’re metabolically healthy, LDL is good for you. Check your insulin sensitivity (homa-ir, or tg/HDL ratio, or fasting insulin) to see what type of ldl you have.

Cholesterol is necessary. You will die without cholesterol. Cholesterol is produced in the liver, delivers fat throughout the body, and then gets recycled in the liver. If something damages the cholesterol during this process, oxidation, or glycation, the LDL will not be recycled by the liver. This is one of the patterns of elevated LDL, it’s the damage LDL that’s the problem, it’s the systematic damage in your body. The LDL isn’t the fault. It’s a symptom. If your LDL isn’t damaged (as seen by insulin sensitivity) then it’s really not a problem.

This joke is beyond gross

If I control your agent, I control what you see, what you say, where you go, everything about your life that touches a computer…

Setting a bad example

Great ideas and well articulated

ED is often a early warning sign of poor metabolic health. Fixing your metabolism will probably fix the ED. Lots of ways to do it, but keto appears to be the most powerful.

Could it indicate something overheated on the other side of the board (the transformer)?