You’d want to also consider, that desktop components were not created for 24/7 usage. My previous motherboard died by overheating south bridge – it likely wouldn’t happen in a desktop usage, but 24/7 didn’t let it cool ever. The chip has a small ‘volcano’ in the middle now.
Stackexchange had a similar answer recently; there are some related links too.
https://space.stackexchange.com/questions/66718/what-if-any-pre-breathes-were-attempted-on-the-iss-and-why