Should I use which file system for Proton and Wine prefixes on Lutris or Steam with an external SSD or microSD card under SteamOS ?
In the Bazzite documentation says “FAT32 and exFAT are unsupported . Both filesystems do not support symbolic links which is required for Proton prefixes to work properly. However, there are scenarios where a microSD card is formatted to exFAT may work in some cases, but this method is unsupported as something the Bazzite maintainers do not plan to accommodate.”


On BTRFS you could use deduplication to make the prefixes take up approximately no extra space. But that requires you to run a deduplication program every once in a while.
Its compression feature can also save some space and decrease load times.
But the impact of this stuff isn’t that big. Much easier to just go ext4 and be done.