Glucagon-like peptide-1 agonism - GLP-1, common in obesity medicines - is not essential to weight management, according to preclinical research led by Richard DiMarchi and Matthias Tschöp, with funding from their startup company Bluewater Biosciences.
And?
Beats the shit out of having to weigh and track every calorie for the rest of your life.
People act like willpower is an infinite resource.
Sounds like a miracle, doesn’t it?
Miracles don’t exist.
What is so different about this than a doctor telling you that this statin will help to lower cholesterol, but if you stop taking it, the cholesterol will come back?
Or a doctor saying that this PDE5 will make your dick hard, but if you stop taking it, you’ll go back to having a limp dick?
I kinda get what you’re saying…but what doctor in their right mind would use that as a reasoning against statins and boner pills?
I think a couple of important things need to be realized…one being that there are a ton of factors that play into obesity.
If you want to cure obesity, it needs to be done at a societal level. You have to be Socratic about it. Nobody ever gets past the first easy “but why” to “what causes obesity.”
Doctors realize this about statins, and they prescribe diet and lifestyle in tandem with statins. Why they can’t apply the same methods to obesity baffles me.
Whataboutisms are wild.
Then original comment said that traditional weight loss isn’t a permanent cure.
Neither are gpl-1s.
And bringing other medications into it is irrelevant.
And of those who do, no one ever gets past the easy pill, that makes corporations rich.
The reason the US in particular doesn’t have the political will to press for the societal change we know will solve things is because it hurts profits of corporations like nestle or General Mills (and many of these mega corps are also profiting off the medical issues the fist creates.)
If GPL1 is the only way it works for you, that’s between you and your doctor, but long term, it’s not a solution. It’s just another subscription making life more expensive than it needs to be
I don’t disagree.
But.
People like you make it sound like sustained weight loss is easy.
It is not. And acting like it is exacerbates the problem.
It is a lifetime of awareness and shutting out signals. It’s maintaining willpower for as long as you can eat solid food. And possibly longer.
Getting weight loss advice from somebody who has never been fat is like taking tax advice from a toddler. Or if MLK were white. You don’t know. You do not understand. That’s fine.
If you’re one of the lucky < 1% who manage to lose weight permanently, great, good for you. You are an exception, not the norm. But you don’t know that yet. Give it a few years. A seemingly small lifestyle change can start setting you back on old habits.
And that’s the next problem, because when it does, it’s a personal failure. And that puts fuel on the fire.
Very, very few people successfully break out of that cycle forever. And they never will without everyone else understanding that obesity is a symptom of a larger issue.
Science is finally starting to look at that, and GLP-1s are a great place to look…because your body also creates GLP-1s to control appetite and regulate digestion. However, the synthetic form tends to stick around longer.
Perhaps, then, one cause of the overeating that leads to obesity is either a deficiency, or a malabsorption of the natural GLP-1s.
In which case, trying to fight that without medication sounds like a losing battle, without first understanding what is causing that. And in which case, saying that people should avoid GLP-1s sounds an awful lot like telling diabetics that they need to stop taking insulin.