Glucagon-like peptide-1 agonism - GLP-1, common in obesity medicines - is not essential to weight management, according to preclinical research led by Richard DiMarchi and Matthias Tschöp, with funding from their startup company Bluewater Biosciences.
i thought we were leaving personal experience and anecdotal evidence out of the discussion, but since you brought it up-- yes i do know. last year i went from 230 lb (my heaviest ever) down to 180 lb. due to other health issues in addition to being way fatter than i’m comfortable with, i decided to eat better at the least, if not always “correctly.” i drastically reduced the junk, sugar, and ultraprocessed food, and did IF (poorly). those few changes brought me from a size 38 pants down to 34.
i love pizza, donuts, french fries, bacon cheeseburgers, and all the other stuff just as much as anyone. no it’s not easy to cut back on those things, and i know the pain of choosing an apple over potato chips. but i’ll say it again (and again and again): “not easy” does NOT equal impossible, and removing agency and responsibility from people is the opposite of helpful
That’s an exceptionally ironic response to scientific studies pointing mapping out the chemical processes behind the above. You’re just desperately trying to justify feeling better than others.
Some people can drop severe drug addictions on their own. Most can’t. Do you treat ex addicts that way too? Tell them it’s agency and responsibility when their fucked up chemical response messes with their head?
If you actually wanted to help others, you’d spend less time condemning people you don’t know and spend more time figuring out why they have problems
i mean, if you’re addicted to heroin, then at some point you’re going to have to make the conscious decision to quit. methadone, rehab, interventions–yea all that stuff can help, but it’s not going to replace people having to make decisions about whether they want to go back to the drugs again
if you insist you’re powerless, then i guess you are. best of luck to you