About half the time recently when printing with PLA, I see that holes or loops have a line of filament running approximately through the middle which seems to be one of the inner perimeters having detached and contracted, but is still attached on both sides. Is it a temperature thing, an extrusion thing? I can’t find a pattern. Bed adhesion is great. Bambu H2C, mostly printing with Bambu Basic PLA.
I would try bumping the flow up manually a bit, and setting it to run slower. Try changing your filament to Generic in the profile too, if it’ll let you.
Then see if you get a few clean layers trying all of this.